Comparison between biokinetics of inhaled plutonium nitrate and gadolinium oxide in humans and animals

Due to the paucity of human data after inhalation of different chemical forms of radionuclides, the implications for human exposure are often based on animal studies. This paper describes biokinetic studies of plutonium nitrate and gadolinium oxide in human volunteers and rats. The results, together with information from other studies with radionuclides, suggests that animal studies can be used with advantage for assessing the biokinetic behavior in humans, and for providing guidance on the assessment of intake and optimal monitoring regimens.