磁场对Schiff碱配合物模拟甲烷单加氧酶催化性能的影响

生命体中存在许多双金属酶 ,其结构和作用机制目前尚不清楚 ,为了模拟甲烷单加氧酶的催化作用 ,我们将催化活性较高的金属卟啉、稳定性较高的 Schiff碱及双核结构结合起来 ,设计合成了一系列“类卟啉型”Schiff碱双核配合物 ,并将这些双核配合物模拟酶催化亚碘酰苯 (Ph IO)单加氧化环己烷反应 ,发现其催化活性及抗氧化稳定性类似于四芳基金属卟啉 [1～ 3 ] ;还发现在模拟酶催化环己烷氧化反应中双核配合物中的两个金属离子间存在协同作用 [4 ] .外加磁场对一般热化学反应影响较小 [5～ 7] ,而在催化反应中的磁场效应更明显 [5,8] .为了较…

Studies on the Influences of Magnetic Fields on the Biocatalytic Properties of Schiff Base Complexes for Monooxygenation of Cyclohexane

The influences of magnetic fields on the biocatalytic properties of Schiff base mono- and dinuclear complexes for the monooxygenation of cyclohexane by PhIO were studied. It was found that the catalytic activities of these catalysts increase with the increase of the outside magnetic field intensity used, and the effects of magnetic field on the catalytic properties of these dinuclear complexes generally increase with the increase of the number of unpaired d electrons of the metal ion and the magnetic exchange between the two metals in these dinuclear complexes. Furthermore, it was found that the effect of magnetic field on the iron complex was greater than that on the other metallic complexes, and the effect of magnetic field on the mononuclear complex was greater than that on the dinuclear complex.