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Developmental iodine deficiency and hypothyroidism impair neural development in rat hippocampus: involvement of doublecortin and NCAM-180
Authors:Jian Gong  Wanyang Liu  Jing Dong  Yi Wang  Hongde Xu  Wei Wei  Jiapeng Zhong  Qi Xi and Jie Chen
Institution:(1) Department of Occupational and Environmental Health, School of Public Health, China Medical University, Shenyang, PR, China;(2) Department of Physiology, the University of Tennessee Health Science Center, 38163 Memphis, TN, USA
Abstract:

Background  

Developmental iodine deficiency results in inadequate thyroid hormone (TH), which damages the hippocampus. Here, we explored the roles of hippocampal doublecortin and neural cell adhesion molecule (NCAM)-180 in developmental iodine deficiency and hypothyroidism.
Keywords:
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