Developmental iodine deficiency and hypothyroidism impair neural development in rat hippocampus: involvement of doublecortin and NCAM-180 |
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Authors: | Jian Gong Wanyang Liu Jing Dong Yi Wang Hongde Xu Wei Wei Jiapeng Zhong Qi Xi and Jie Chen |
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Institution: | (1) Department of Occupational and Environmental Health, School of Public Health, China Medical University, Shenyang, PR, China;(2) Department of Physiology, the University of Tennessee Health Science Center, 38163 Memphis, TN, USA |
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Abstract: | Background Developmental iodine deficiency results in inadequate thyroid hormone (TH), which damages the hippocampus. Here, we explored
the roles of hippocampal doublecortin and neural cell adhesion molecule (NCAM)-180 in developmental iodine deficiency and
hypothyroidism. |
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Keywords: | |
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