Tyrosinase-inhibitory long-chain esters from Amberboa ramosa |
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| Authors: | Khan Sher Bahadar Azhar-Ul-Haq Afza Nighat Malik Abdul Khan Mahmud Tariq Hasan Shah Muhammad Raza Choudhary Muhammad Iqbal |
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| Institution: | International Center for Chemical Sciences, H.E.J. Research Institute of Chemistry, University of Karachi, Karachi, Pakistan. |
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| Abstract: | Long-chain esters 1 and 2 have been isolated from the chloroform-soluble fraction of Amberboa ramosa and their structures assigned to be methyl 2beta(2S)-hydroxyl-7(E)-tritriacontenoate (1) and methyl 2beta(2S)-O-beta-D-galactopyranosyl-7(E)-tetratriacontenoate (2). In addition, tricontane (3) and apigenin (4) are also reported for the first time from this species. The structures were assigned on the basis of 1D and 2D NMR techniques. Compounds 1 and 2 showed strong to moderate inhibitory activity against tyrosinase. |
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