Synthesis of Ultra‐Stable Fluorescent Carbon Dots from Polyvinylpyrrolidone and Their Application in the Detection of Hydroxyl Radicals |
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Authors: | Xiangling Ren Jing Liu Dr Xianwei Meng Jianfei Wei Dr Tianlong Liu Prof Fangqiong Tang |
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Institution: | 1. Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, 29 Zhongguancun East Road, Haidian District, Beijing, 100190 (P.R. China), Fax: (+86)?10‐62554670;2. University of Chinese Academy of Sciences, Beijing 100049 (P.R. China) |
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Abstract: | Highly biocompatible and highly photostable fluorescent carbon dots (C dots) were obtained through a simple and nontoxic one‐pot hydrothermal method. Polyvinylpyrrolidone, a common and low‐cost biocompatibility reagent, was used as the only carbon source for the first time. The resulting water‐soluble C dots showed a quantum yield of up to 23.58 % with low cytotoxicity, favorable photoluminescent properties, and good photostability. Importantly, the fluorescence intensities of the C dots were quite stable in high‐salt conditions and over a broad pH range (3.0–10.5). The as‐prepared C dots have been demonstrated to be an excellent probe for hydroxyl radicals sensing based on the fluorescence quenching with great sensitivity and specificity. This opens up a new application field for C dots. |
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Keywords: | carbon fluorescent probes hydrothermal synthesis nanostructures radicals |
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