轻中度铅中毒儿童的干预治疗

为探讨轻中度铅中毒儿童的干预治疗的方法 ,将 96例血铅水平 10 0～ 4 0 0 μg/L的铅中毒儿童随机分成三组 :对照组为健康教育组 ;治疗A组为服钙组 ;治疗B组为混合组 :服食钙剂的同时 ,配合进行有关的健康教育。分别干预三个月后复查血铅水平。结果表明 ,三组儿童干预前后的血铅水平分别为 :对照组 (n =30 ) 2 0 6 0± 6 6 0 μg/L ,134 2± 4 2 9μg/L ,下降了 35% ;治疗A组(n =34) 2 0 8 5± 6 0 3μg/L ,12 4 0± 4 0 7μg/L ,下降了 4 1% ;治疗B组 (n =32 ) 2 2 5 9± 70 4 μg/L ,10 8 4± 33 8μg/L ,下降了 52 %。干预前各组间血铅水平没有差异 (P >0 0 5) ,而干预后对照组与治疗A组、对照组与治疗B组间比较 ,t分别为 0 970 (P >0 0 5)、2 6 36 (P <0 0 1) ,对照组与治疗B组之间有显著差异。提示健康教育及口服钙剂皆能明显降低轻中度铅中毒儿童的血铅水平 ,而两者同时配合进行 ,效果更加显著。

Investigation of Intervention on Children with Light and Moderate Lead Poisoning

To explore the methods of intervention therapy in the slight and moderate lead poisoning，96 cases with lead poisoning children which blood lead level was 100～400 μg/L were divided into three groups randomly:health (health education) contrast group,therapy group A (taking calcium) and therapy group B (health education and taking calcium).The blood lead levels were determined after three months.The results showed that the blood lead level before and after intervention of the three groups were：contrast group 206.4±66.0 μg/L and 134.2±42.9 μg/L,dropped 35%，therapy group A 208.5±60.3 μg/L and 124.0±40.7 μg/L,dropped 41%;therapy group B 225.9±70.4 μg/L and 108.4±33.8 μg/L, dropped 52%,the blood level was obviously reduced in these three groups children.After intervention,there was no difference between contrast group and therapy group A(t=0.970,P＞0.05),but there were significant difference between contrast group and therapy group B(t=2.636，P＜0.01).It concluded that health education or taking calcium can obviously reduce the blood lead level of children with the slight and moderate lead poisoning and the effect was notable that cooperating with them at the same time.