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Triplex-directed covalent cross-linking of a DNA nanostructure
Authors:David A Rusling  Iris S Nandhakumar  Tom Brown  Keith R Fox
Affiliation:Centre for Biological Sciences, University of Southampton, Highfield, Southampton, UK. K.R.Fox@soton.ac.uk D.A.Rusling@soton.ac.uk.
Abstract:The triplex approach to DNA recognition is exploited to direct covalent inter-strand cross-links to unique locations within a pre-assembled DNA nanostructure. This approach can be used to improve the stability of DNA nanostructures and demonstrates the feasibility of directing other reactive groups to unique locations within these complexes.
Keywords:
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