A liquid-phase peptide synthesis in cyclohexane-based biphasic thermomorphic systems |
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| Authors: | Chiba Kazuhiro Kono Yusuke Kim Shokaku Nishimoto Kohsuke Kitano Yoshikazu Tada Masahiro |
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| Affiliation: | Laboratory of Bio-Organic Chemistry, Tokyo University of Agriculture and Technology, 3-5-8 Saiwai-cho, Fuchu, Tokyo 183-8509, Japan. chiba@cc.tuat.ac.jp |
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| Abstract: | Combinations of typical organic solvents composed of cyclohexane and qualified aprotic polar organic solvents were found to realize an effective, biphasic thermomorphic system in arbitrary ratios of upper and lower phases that enable a practical application of a liquid-phase peptide synthesis. |
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