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Preparation of biohybrid amphiphiles via the copper catalysed Huisgen [3 + 2] dipolar cycloaddition reaction
Authors:Dirks A J Ton  van Berkel Sander S  Hatzakis Nikos S  Opsteen Joost A  van Delft Floris L  Cornelissen Jeroen J L M  Rowan Alan E  van Hest Jan C M  Rutjes Floris P J T  Nolte Roeland J M
Institution:Institute for Molecules and Materials, Radboud University Nijmegen, Toernooiveld 1, 6525 ED Nijmegen, The Netherlands.
Abstract:Biohybrid amphiphiles have been prepared from terminal azide functionalised polystyrene and an alkyne functionalised peptide or protein via a Cu(I) catalysed Huisgen 3 + 2] dipolar cycloaddition reaction.
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