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Antifungal effects of secondary metabolites isolated from marine organisms collected from the Tunisian coast
Authors:Saoussen Hammami  Afifa Bergaoui  Naima Boughalleb  Anis Romdhane  Ines Khoja  Monia Ben Halima Kamel  Zine Mighri
Institution:1. Laboratoire de chimie des substances naturelles et de synthèse organique (99, UR/12-26), 5000 Monastir, Tunisia;2. Laboratoire de phytopathologie, institut supérieur agronomique de Chott Mariem, 4042 Sousse, Tunisia;3. Invertebrate, micro-organism, harmful weeds alternative struggle, High School of Horticulture and Animal Production Chott Mariem, 4042 Sousse, Tunisia
Abstract:Phallusides 1,2,3 (1), Fasciculatin (2), Acanthelline (3), Axisonitrile (4), Oroïdin (5) and the Novel bromopyrolimidazolic compound Axinellizine (6) were evaluated for their antifungal effects against several phytopatogenic fungi and were found to possess considerable activities. Insecticidal effect of only Acanthellin (3) against the major pest of stored products Tribolium confusum Duv has been carried out using direct contact application method showing a significant inhibitory effect of the test material on the T. confusum Duv larvae growth. Forty-five percent mortality of the adults was achieved 8 days after treatment.
Keywords:Sponges  Tunicate  Secondary metabolites  Antifungal effects  Insecticidal activity
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