Azomethine ylide mediated inversion of configuration of quaternary imidazoline carbon: converting trans- to its cis- imidazolines |
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| Authors: | Qu Ke Fisk Jason S Tepe Jetze J |
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| Institution: | Department of Chemistry, Michigan State University, East Lansing, MI 48824, United States |
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| Abstract: | An efficient synthetic methodology of converting trans-4,5-diaryl-2-imidazolines to the corresponding cis-4,5-diaryl-2-imidazolines has been developed. This methodology features mild reaction conditions and a simple one-pot two-step procedure. |
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| Keywords: | Cancer treatment Azomethine ylide Imidazoline Oxazolone |
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