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Antimicrobial screening and quantitative determination of benzoic acid derivative of Gomphrena celosioides by TLC-densitometry
Authors:de Moura Rute Mendonça Xavier  Pereira Paulo Sérgio  Januário Ana Helena  França Suzelei de Castro  Dias Diones Aparecida
Affiliation:Departamento de Química, Faculdade de Filosofia, Ciências e Letras de Ribeir?o Preto, Universidade de S?o Paulo, 14040-020 Ribeir?o Preto, S?o Paulo, Brazil.
Abstract:The antimicrobial activity of ethanolic extract and pure compounds of Gomphrena celosioides have been screened by Kirby-Bauer method. Quantitative determination of 4-hydroxy-3-methoxy-benzoic acid in stems, leaves, flowers and roots was established by TLC-densitometry. Results showed significant activity against Staphylococcus aureus and Salmonella typhi. There were no significant differences in the determined benzoic acid derivative.
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