Metalation of 2-Methyl-N-phenylbenzamide withn-butyllithium. Formation ofN,3-diphenyl-1-isoquinolinamine by subsequent reaction with benzonitrile |
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Authors: | Tonson Abraham |
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Affiliation: | (1) Universal Energy Systems, Inc., 45432 Dayton, OH, USA;(2) Present address: Research Institute, University of Dayton, 300 College Park, 45469 Dayton, OH, USA |
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Abstract: | 2-Methyl-N-phenylbenzamide was metalated with two equivalents ofn-butyllithium. Benzonitrile was allowed to react with the organometalic intermediate thus formed to yieldN,3-diphenyl-1-isoquinolinamine.
Metallierung von 2-Methyl-N-phenyl-benzamid mitn-Butyllithium und Bildung vonN,3-Diphenyl-1-isochinolinamin durch anschließende Reaktion mit Benzonitril Zusammenfassung Reaktion von Benzonitril mit der Di-Lithiumverbindung aus 2-Methyl-N-phenylbenzamid und 2 moln-Butyllithium liefertN,3-Diphenyl-1-isochinolinamin. |
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Keywords: | Benzamide, iminophenylethyl-phenyl Cyclodehydration Isoquinolinamine, diphenyl Lithiation |
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