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High performance liquid chromatographic analysis of theIn vitro N-dealkylated andN-oxide metabolites ofN-ethyl-N-methylaniline: Methodology for the determination of enzyme activity and stereoselectivity ofN-oxidation
Authors:M. R. Hadley  H. G. Oldham  L. A. Damani  A. J. Hutt
Affiliation:1. Department of Analytical Sciences, SmithKline Beecham Pharmaceuticals, Old Powder Mills, TN11 9AN, Tombridge, Kent, UK
2. Department of Drug Metabolism and Pharmacokinetics, SmithKline Beecham Pharmaceuticals, The Frythe, AL6 9AR, Welwyn, Herts, UK
3. Department of Pharmacy, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong
4. Department of Pharmacy, King's College London, Manresa Road, SW3 6LX, London, UK
Abstract:
Keywords:
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