Discovery of long-wavelength photoactivatable diaryltetrazoles for bioorthogonal 1,3-dipolar cycloaddition reactions |
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| Authors: | Wang Yizhong Hu Wen J Song Wenjiao Lim Reyna K V Lin Qing |
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| Affiliation: | Department of Chemistry, State University of New York at Buffalo, Buffalo, New York 14260, USA. |
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| Abstract: | Several long-wavelength (365 nm) photoactivatable diaryltetrazoles were discovered by screening a series of substituted diaryltetrazoles and subsequently showed excellent reactivity in the photoactivated 1,3-dipolar cycloaddition reactions toward electron-deficient and conjugated alkenes in organic solvents as well as an alkene-containing protein in the aqueous buffer. |
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