Enantioselective synthesis of tetrafluorinated glucose and galactose |
| |
Authors: | Timofte Roxana S Linclau Bruno |
| |
Institution: | University of Southampton, School of Chemistry, Highfield, Southampton SO17 1BJ. |
| |
Abstract: | Polyfluorinated carbohydrates have emerged as interesting probes to investigate "polar hydrophobicity" effect(s) in protein-carbohydrate interactions. A convenient enantioselective synthesis of tetrafluorinated analogues of two of the most important monosaccharides, D-glucose and D-galactose, is reported, as well as our first results regarding the glycosylation of these sugar analogues. |
| |
Keywords: | |
本文献已被 PubMed 等数据库收录! |
|