Asymmetric synthesis of ceramide sphingolipid based on (2S,3S,4S)-3,4-dihydroxy-5-(hydroxymethyl)pyrrolidine lactam |
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Authors: | Wen-Feng Huang Lu-Men Chao Bang-Guo Wei |
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Affiliation: | a Department of Chemistry, Fudan University, 220 Handan Road, Shanghai 200433, China b School of Pharmacy, Fudan University, 826 Zhangheng Road, Shanghai 201203, China |
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Abstract: | A facile approach to the versatile chiral building block 2 was developed based on glutamic acid, whereby a new method for asymmetric synthesis of sex pheromone 1 was explored from cheap glutamic acid. |
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Keywords: | Pheromone Sphingolipid Ceramide Lactam Asymmetric synthesis |
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