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Lyngbyacyclamides A and B, novel cytotoxic peptides from marine cyanobacteria Lyngbya sp.
Authors:Norihito Maru  Daisuke Uemura
Institution:a Department of Biosciences and Informatics, Keio University, 3-14-1 Hiyoshi, Yokohama 223 8522, Japan
b Department of Chemistry, Keio University, 3-14-1 Hiyoshi, Yokohama 223 8522, Japan
Abstract:Lyngbyacyclamides A (1) and B (2), novel cyclic peptides, were isolated from marine cyanobacteria Lyngbya sp. collected in Okinawa, Japan. Their structures were determined by spectroscopic analyses and degradation studies. They moderately inhibited the growth of B16 mouse melanoma cells.
Keywords:Lyngbyacyclamide A  Lyngbya sp    Cytotoxicity  Cyclic peptide
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