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High yielding microwave-assisted synthesis of 2-(arylmethyl)amino-4-arylamino-6-alkyl-1,3,5-triazines
Authors:Huixiong Chen  Pascal Dao  Alice Laporte  Christiane Garbay
Institution:Laboratoire de Chimie et Biochimie Pharmacologiques et Toxicologiques, CNRS UMR 8601, UFR Biomédicale, Université Paris Descartes, 45 rue des Saints Pères, 75270 Paris Cedex 06, France
Abstract:An efficient and practical procedure was developed to prepare novel 2-(arylmethyl)amino-4-arylamino-6-alkyl-1,3,5-triazines, starting from dicyandiamide and the corresponding arylamines under microwave irradiation and its scope is demonstrated with a number of examples. The valuable feature of this procedure included the short reaction times, high yields, and easy operation.
Keywords:2-(Arylmethyl)amino-4-arylamino-6-alkyl-1  3  5-triazines  Microwave synthesis  Cyclocondensation
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