High yielding microwave-assisted synthesis of 2-(arylmethyl)amino-4-arylamino-6-alkyl-1,3,5-triazines |
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Authors: | Huixiong Chen Pascal Dao Alice Laporte Christiane Garbay |
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Institution: | Laboratoire de Chimie et Biochimie Pharmacologiques et Toxicologiques, CNRS UMR 8601, UFR Biomédicale, Université Paris Descartes, 45 rue des Saints Pères, 75270 Paris Cedex 06, France |
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Abstract: | An efficient and practical procedure was developed to prepare novel 2-(arylmethyl)amino-4-arylamino-6-alkyl-1,3,5-triazines, starting from dicyandiamide and the corresponding arylamines under microwave irradiation and its scope is demonstrated with a number of examples. The valuable feature of this procedure included the short reaction times, high yields, and easy operation. |
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Keywords: | 2-(Arylmethyl)amino-4-arylamino-6-alkyl-1 3 5-triazines Microwave synthesis Cyclocondensation |
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