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Synthesis of new difluoroalkyl propargylic ketones and their use for the preparation of fluorinated heterocycles |
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| Authors: | Pierre Bannwarth |
| Affiliation: | Université de Rennes 1, Laboratoire de Chimie et Photonique Moléculaires, CNRS UMR 6510 et Laboratoire Sciences Chimiques de Rennes, CNRS UMR 6226, Avenue du Général Leclerc, 35042 Rennes Cedex, France |
| Abstract: | Synthetic methodology studies are reported towards the preparation of new propargylic ketones with CF2R side chains. These molecules are used for the synthesis of various types of five- or six-membered heterocycles with difluoroalkyl side chains. |
| Keywords: | Fluorine Difluoralkyl compounds Propargylic ketones Cyclocondensation reactions Pyrimidines Pyridines Pyrazoles Isoxazoles |
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