An improved protocol for Petasis reaction of 2-pyridinecarbaldehydes |
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| Authors: | Hiroki Mandai Kyouta Murota Takashi Sakai |
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| Institution: | Division of Chemistry and Biochemistry, Graduate School of Natural Science and Technology, Okayama University, 3-1-1 Tsushima-naka, Kita-ku, Okayama 700-8530, Japan |
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| Abstract: | A highly efficient and improved method has been developed for Petasis reactions of various 2-pyridinecarbaldehydes with secondary amines and boronic acids under catalyst-free conditions. The desired products are obtained in up to 96% yield in refluxed acetonitrile. |
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