Microwave-assisted amination of 3-bromo-2-chloropyridine with various substituted aminoethanols |
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| Authors: | Jeong Geun Kim Woo Sup Youn Deok-Chan Ha |
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| Institution: | a Department of Chemistry, Korea University, Sungbuk-gu, Seoul 136-701, Republic of Korea
b Bio-Organic Science Division, Korea Research Institute of Chemical Technology, Daejeon 305-600, Republic of Korea |
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| Abstract: | A simple method for microwave-assisted amination of 3-bromo-2-chloropyridine with various substituted aminoethanols is described. The reaction was carried out under microwave irradiation conditions (at 180 °C for 1-2 h) and the result was superior in terms of conversion and yield when compared to that of the corresponding conventional heating conditions. |
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| Keywords: | Microwave-assisted amination 3-Bromo-2-chloropyridine Aminoethanol Pyrido[1 4]oxazine |
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