Synthesis of highly functionalized piperidines by one-pot multicomponent reaction using tetrabutylammonium tribromide (TBATB) |
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| Authors: | Abu T Khan Mohan Lal Md Musawwer Khan |
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| Institution: | Department of Chemistry, Indian Institute of Technology Guwahati, Guwahati 781 039, India |
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| Abstract: | Tetrabutylammonium tribromide (TBATB) has been found to be an efficient catalyst for the one-pot synthesis of highly substituted piperidines through a combination of 1,3-dicarbonyl compounds, aromatic aldehydes, and various amines in ethanol at room temperature. Atom economy, good yields, environmentally benign, and mild reaction conditions are some of the important features of this protocol. |
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| Keywords: | TBATB Heterocycles Piperidines Multicomponent reactions 1 3-Dicarbonyl compounds |
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