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First immobilization of a glycoluril-derived molecular clip on Merrifield resin: facile separation of dihydroxybenzenes by affinity chromatography
Authors:Esmail Rezaei-Seresht  Fahimeh Hokmabadi
Affiliation:Department of Chemistry, Faculty of Sciences, Sabzevar Tarbiat Moallem University, Towhidshahr, Sabzevar 96179-76487, Iran
Abstract:A practical method for the separation and purification of dihydroxybenzenes from phenol-dihydroxybenzene, methoxyphenol-dihydroxybenzene, and isomeric dihydroxybenzene mixtures was developed on the basis of affinity chromatography using a functionalized Merrifield resin. The resin was obtained by immobilization of a glycoluril-derived clip on Merrifield resin. This recyclable resin was repeatedly used for convenient and rapid separation of dihydroxybenzenes from the above-mentioned mixtures.
Keywords:Glycoluril clip   Immobilization   Merrifield resin   Dihydroxybenzenes   Affinity chromatography
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