An elegant approach for stereocontrolled synthesis of furopyran building blocks |
| |
Authors: | U Murali Krishna |
| |
Institution: | Department of Surgery and Biomedical Engineering, Emory University School of Medicine, Atlanta, GA 30322, United States |
| |
Abstract: | An elegant approach for stereocontrolled synthesis of furopyran (hexahydro-2H-furo3,2-b]pyran) building blocks was reported. The key steps in the sequence involved an efficient intramolecular 3-oxidopyrylium-alkene 5+2] cycloaddition for the synthesis of cycloadduct 6 and Beckmann fragmentation of ketoxime 13 to yield the furopyrans (5a-c). |
| |
Keywords: | 3-Oxidopyrylium [5+2] Cycloaddition Ketoxime Beckmann fragmentation Furopyran |
本文献已被 ScienceDirect 等数据库收录! |