Bisleucocurine A, a novel bisindole alkaloid from Leuconotis griffithii |
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| Authors: | Alfarius E Nugroho Takahiro Hosoya A Hamid A Hadi |
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| Institution: | a Faculty of Pharmaceutical Sciences, Hoshi University, Ebara 2-4-41 Shinagawa-ku, Tokyo 142-8501, Japan
b Department of Chemistry, Faculty of Science, University of Malaya, 50603 Kuala Lumpur, Malaysia |
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| Abstract: | A novel bisindole alkaloid, bisleucocurine A (1), consisting of two strychnan skeletons with an N-1-C-17′ and a C-12-C-2′ bridges, was isolated from the leaves of Leuconotis griffithii and the structure was elucidated on the basis of spectroscopic data. Bisleucocurine A (1) showed cytotoxicity against various human cancer cell lines. |
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