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Direct C-H bond arylation of 2-hydroxybenzaldehydes with arylboronic acids via ligand-free palladium catalysis
Authors:Fei Weng
Affiliation:Department of Chemistry, Shanghai University, Shanghai 200444, China
Abstract:A mild and efficient ligand-free palladium-catalyzed direct C-H bond arylation reaction was developed to afford 2-hydroxybenzophenones in good to excellent yields from easily available 2-hydroxybenzaldehydes and arylboronic acids. The given reaction provided one of the easiest pathways for accessing 2-hydroxybenzophenones, and a variety of functional groups could be tolerated in this process.
Keywords:Arylboronic acids   C-H Bond arylation   2-Hydroxybenzaldehydes   2-Hydroxybenzophenones   Palladium-catalyzed
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