Biorecognition-modulated ion fluxes through functionalized gold nanotubules as a novel label-free biosensing approach |
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Authors: | Gyurcsányi Robert E Vigassy Tamás Pretsch Ernö |
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Institution: | Laboratorium für Organische Chemie, ETH H?nggerberg, HCI E 313, CH-8093 Zürich, Switzerland. robertgy@mail.bme.hu |
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Abstract: | A novel biosensing principle is presented, based on the potentiometric monitoring of an indicator ion such as Ca2+, whose zero-current flux through chemically modified nanochannels is altered by biorecognition events. |
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