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A novel four-component reaction for the synthesis of functionalised dihydropyrimidines
Authors:Vugts Danielle J  Jansen Helen  Schmitz Rob F  de Kanter Frans J J  Orru Romano V A
Affiliation:Department of Chemistry, Vrije Universiteit Amsterdam, De Boelelaan 1083, 1081 HV Amsterdam, The Netherlands.
Abstract:In a multi-component reaction (MCR) of a phosphonate, nitriles, aldehydes and isocyanates, N3-functionalised dihydropyrimidines can be synthesised efficiently via a Horner-Emmons/aza Diels-Alder pathway.
Keywords:
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