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Addressing Protein–Protein Interactions with Small Molecules: A Pro‐Pro Dipeptide Mimic with a PPII Helix Conformation as a Module for the Synthesis of PRD‐Binding Ligands |
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| Authors: | Dr. Jan Zaminer Dr. Christoph Brockmann Dipl.‐Chem. Peter Huy Dipl.‐Biophys. Robert Opitz Dipl.‐Chem. Cédric Reuter Dr. Michael Beyermann Priv.‐Doz. Dr. Christian Freund Dipl.‐Biochem. Matthias Müller Prof. Dr. Hartmut Oschkinat Dr. Ronald Kühne Prof. Dr. Hans‐Günther Schmalz |
| Affiliation: | 1. Universit?t zu K?ln, Department für Chemie, Greinstrasse 4, 50939 K?ln (Germany), Fax: (+49)?221‐470‐3064;2. Leibniz‐Institut für Molekulare Pharmakologie, Robert‐R?ssle‐Strasse 10, 13125 Berlin (Germany) |
| Abstract: | |
| Keywords: | conformational analysis molecular modeling peptide mimics protein– protein interactions ring‐closing metathesis |