Multicomponent Reactions for the Synthesis of Heterocycles |
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Authors: | Dr. Bo Jiang Trideep Rajale Walter Wever Prof. Dr. Shu‐Jiang Tu Prof. Dr. Guigen Li |
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Affiliation: | 1. School of Chemistry and Chemical Engineering, Xuzhou Normal University, Xuzhou 221116, Jiangsu, (P. R. China), Fax: (+86)‐516‐83500065;2. Department of Chemistry and Biochemistry, Texas Tech University, Lubbock, TX 79409‐1061 (USA), Fax: (+1)?806‐742‐1289 |
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Abstract: | Multicomponent domino reactions (MDRs) serve as a rapid and efficient tool for the synthesis of versatile heterocycles, particularly those containing structural diversity and complexity, by a one‐pot operation. These reactions can dramatically reduce the generation of chemical wastes, costs of starting materials, and the use of energy and manpower. Moreover, the reaction period can be substantially shortened. This Review covers recent advances on multicomponent domino reactions for the construction of five‐, six‐, and seven‐membered heterocyclic skeletons and their multicyclic derivatives. |
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Keywords: | domino reactions green chemistry heterocycles microwave irradiation multicomponent reactions |
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