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Silver‐Catalyzed Benzylation and Allylation of Tertiary Alkyl Bromides with Organozinc Reagents |
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| Authors: | Yukihiro Mitamura Yoshihiro Asada Kei Murakami Hidenori Someya Hideki Yorimitsu Prof?Dr Koichiro Oshima Prof?Dr |
| Institution: | Department of Material Chemistry, Graduate School of Engineering, Kyoto University, Kyoto‐daigaku Katsura, Nishikyo, Kyoto 615‐8510 (Japan), Fax: (+81)?75‐383‐2438 |
| Abstract: | Silver salts catalyze the benzylation and allylation of tertiary alkyl bromides with organozinc reagents. The reactions create quaternary carbon centers efficiently. Treatment of gem‐dibromoalkanes with benzylic or allylic zinc reagents under silver catalysis leads to dibenzylation or diallylation. The functional‐group compatibility of the present reactions is wider than that of the previous reactions with Grignard reagents. |
| Keywords: | alkyl halides allylation benzylation organozinc reagents silver |