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Oxidation of N-substituted dopamine derivatives: irreversible formation of a spirocyclic product
Authors:Land Edward J  Perona Almudena  Ramsden Christopher A  Riley Patrick A
Institution:School of Chemistry and Physics, Keele University, Keele, Staffordshire, UKST5 5BG.
Abstract:Oxidation of amide, urea and guanidinium derivatives of dopamine gives relatively stable ortho-quinones whereas oxidation of corresponding thioamide and amidinium derivatives rapidly and quantitatively gives novel bicyclic and spirocyclic products formed via the corresponding ortho-quinone.
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