Synthesis, crystal structure, and antitumor activity of the cadmium dichloride complex with semicarbazide |
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| Authors: | B. S. Fedorov M. A. Fadeev A. N. Utenyshev G. V. Shilov N. P. Konovalova L. V. Tat’yanenko T. E. Sashenkova S. V. Blokhina E. N. Berseneva |
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| Affiliation: | 1. Institute of Problems of Chemical Physics, Russian Academy of Sciences, 1 prosp. Akad. Semenova, 142432, Chernogolovka, Moscow Region, Russian Federation
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| Abstract: | The chelate cadmium dichloride complex with semicarbazide was synthesized. The use of this complex in the cytostatic combination therapy together with cyclophosphamide results in 67% survival of mice and a threefold increase in the average life span of survivors with P-388 leukemia. |
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