Analysis of crystal and three dimensional structures of drug substances |
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| Authors: | I. G. Smirnova G. N. Gil’deeva V. V. Chistyakov |
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| Affiliation: | 1. Department of Natural Compound Chemistry, Moscow State University, Moscow, Russia
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| Abstract: | The alteration of a crystalline state or the optical isomerism of a substance significantly affects the physicochemical, pharmacotechnological properties, and bioavailability of drugs. It was shown that X-Ray powder diffraction, infrared Fourier spectroscopy, differential scanning calorimetry, optical microscopy, and circular dichroism methods can be successfully used for the quality control of drug substances. |
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