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Superparamagnetic nanoparticle-supported enzymatic resolution of racemic carboxylates
Authors:Gardimalla Hari M R  Mandal Deendayal  Stevens Philip D  Yen Max  Gao Yong
Affiliation:Department of Chemistry and Biochemistry, Mailcode 4409, Southern Illinois University, Carbondale, IL 62901-4409, USA.
Abstract:Candida rugosa lipase immobilized on maghemite nanoparticles demonstrated high stereoselectivity in kinetic resolution of racemic carboxylates and improved long-term stability over its parent free enzyme, allowing the supported enzyme to be repeatedly used for a series of chiral resolution reactions.
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