A simple and highly efficient synthesis of N-phenyl-2-polyfluoroalkyl-4-quinolones from 2-anilinoacetophenone and RFCO2Et |
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Authors: | Boris I. Usachev |
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Affiliation: | Department of Chemistry, Ural State University, Lenina 51, Ekaterinburg 620083, Russia |
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Abstract: | The condensation of 2-anilinoacetophenone with RFCO2Et (RF = CF2H, CF3, C2F5) in the presence of LiH in THF affords the corresponding N-phenyl-2-polyfluoroalkyl-4-quinolones in excellent yields. |
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Keywords: | Condensation 2-Anilinoacetophenone Polyfluorocarboxylic esters N-phenyl-2-polyfluoroalkyl-4-quinolones |
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