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A simple and highly efficient synthesis of N-phenyl-2-polyfluoroalkyl-4-quinolones from 2-anilinoacetophenone and RFCO2Et
Authors:Boris I Usachev
Institution:Department of Chemistry, Ural State University, Lenina 51, Ekaterinburg 620083, Russia
Abstract:The condensation of 2-anilinoacetophenone with RFCO2Et (RF = CF2H, CF3, C2F5) in the presence of LiH in THF affords the corresponding N-phenyl-2-polyfluoroalkyl-4-quinolones in excellent yields.
Keywords:Condensation  2-Anilinoacetophenone  Polyfluorocarboxylic esters  N-phenyl-2-polyfluoroalkyl-4-quinolones
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