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Introduction of several trifluoromethyl groups onto the activated aromatic materials with CF3TMS-CuI-KF system
Authors:Tomoya Kitazume  Satoshi Nakajima
Affiliation:Graduate School of Biosceince & Biotechnology, Tokyo Institute of Technology, 4259 Nagatsuta, Midori-ku Yokohama 226-8501, Japan
Abstract:Trifluoromethylation onto the tetrafluorophthalonitrile and tetrafluoroisophthalonitrile has been carried out using CF3TMS-CuI-KF system, and it was demonstrated that these trifluoromethylation enabled us to successfully construct di- and/or tri-trifluoromethylated benzonitriles via the decyanotrifluoromethylation.
Keywords:Trifluoromethylation   Decyanotrifluoromethylation   Multitrifluoromethylation
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