Introduction of several trifluoromethyl groups onto the activated aromatic materials with CF3TMS-CuI-KF system |
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Authors: | Tomoya Kitazume Satoshi Nakajima |
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Affiliation: | Graduate School of Biosceince & Biotechnology, Tokyo Institute of Technology, 4259 Nagatsuta, Midori-ku Yokohama 226-8501, Japan |
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Abstract: | Trifluoromethylation onto the tetrafluorophthalonitrile and tetrafluoroisophthalonitrile has been carried out using CF3TMS-CuI-KF system, and it was demonstrated that these trifluoromethylation enabled us to successfully construct di- and/or tri-trifluoromethylated benzonitriles via the decyanotrifluoromethylation. |
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Keywords: | Trifluoromethylation Decyanotrifluoromethylation Multitrifluoromethylation |
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