Enantioselective synthesis of 3,3-disubstituted oxindoles through Pd-catalyzed cyanoamidation |
| |
| Authors: | Yasui Yoshizumi Kamisaki Haruhi Takemoto Yoshiji |
| |
| Institution: | Graduate School of Pharmaceutical Sciences, Kyoto University, Yoshida, Sakyo-ku, Kyoto 606-8501, Japan. |
| |
| Abstract: | The first enantioselective cyanoamidation of olefins provides quick access to a variety of 3,3-disubstituted oxindoles. The combination of Pd(dba)2, an optically active phosphoramidite, and N, N-dimethylpropylene urea (DMPU) in decalin were found to be the best conditions. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
|
