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Electrochemical Behavior of Herbal Antitumor Drug Aloe‐Emodin at Carbon‐Coated Nickel Magnetic Nanoparticles Modified Glassy Carbon Electrode
Authors:Chunli Bian  Lin Zhang  Huayu Xiong  Xiuhua Zhang  Shengfu Wang
Institution:1. Ministry of Education Key Laboratory for the Synthesis and Application of Organic Functional Molecules & College of Chemistry and Chemical Engineering, Hubei University, Wuhan 430062, P.?R. China tel.: +86‐27‐50865309;2. fax: +86‐27‐88663043
Abstract:The electrochemical behavior of aloe‐emodin (AE), an important herbal antitumor drug, was investigated at a carbon‐coated nickel magnetic nanoparticles modified glassy carbon electrode (CNN/GCE). A couple of well‐defined redox peaks was obtained. Some electrochemical parameters of AE at a CNN/GCE, such as the charge number, exchange current density, standard heterogeneous rate constant, were measured. The square wave voltammetry (SWV) response of AE was linear with the concentration over two concentration intervals viz. 6.24×10?9?1.13×10?6 M and 1.13×10?6?1.23×10?5 M, with a detection limit of 2.08 nM. A fast, simple and sensitive detection and analysis of AE was developed.
Keywords:Aloe‐emodin  Voltammetry  Carbon‐coated nickel  Magnetic nanoparticles  Electrochemical determination
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