Two New Metabolites,Epoxydine A and B,from Phoma sp. |
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| Authors: | Song Qin Hidayat Hussain Barbara Schulz Siegfried Draeger Karsten Krohn |
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| Affiliation: | 1. Department Chemie, Universit?t Paderborn, Warburger Stra?e 100, D‐33098 Paderborn, (fax: +49‐5251‐60‐3245);2. Institut für Mikrobiologie, Technische Universit?t Braunschweig, Spielmannstra?e 7, D‐31806 Braunschweig |
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| Abstract: | The new compounds, epoxydines A and B ( 1 and 2 , resp.), along with the known and related metabolites, 3 – 6 , were isolated from the fungal endophyte Phoma sp. The structures of the new compounds were elucidated by detailed spectroscopic analysis, and the relative configuration of 1 was confirmed by ROESY experiments. Preliminary studies indicated that compounds 2 – 5 possess good antibacterial, antifungal, and algicidal properties. Similarly, compound 1 showed antifungal and algicidal, and compound 6 antibacterial and algicidal properties. |
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| Keywords: | Phoma species Salsola oppostifolia Epoxydines A and B Metabolites Antibacterial activity Antifungal activity Algicidal activity |
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