Glucose Biosensor Based on Silicon Nitride Nanoparticles |
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Authors: | Abdollah Salimi Roaya Zand‐Karimi Abdollah Noorbakhash Saied Soltanian |
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Affiliation: | 1. Department of Chemistry, University of Kurdistan, P.?O.Box 416, Sanandaj, Iran;2. Research Center for Nanotechnology, University of , Kurdistan , P.?O.Box 416, Sanandaj, Iran tel: +98‐871‐6660075, fax: +98‐871‐6624001 |
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Abstract: | For the first time silicon nitride (Si3N4) nanoparticles was used for preparation electrochemical biosensor. GOx immobilized on the Si3N4 nanoparticles exhibits facile and direct electrochemistry. The surface coverage and heterogeneous electron transfer rate constant (ks) of immobilized GOx were 6.3×10?13 mol cm?2 and 47.4±0.3 s?1. The sensitivity, linear concentration range and detection limit of the biosensor for glucose detection were 38.57 µA mM?1 cm?2, 25 µM to 8 mM and 6.5 µM, respectively. This biosensor also exhibits good stability, reproducibility and long life time. These indicate Si3N4 nanoparticles is good candidate material for construction of third generation biosensor and bioelectronics devices. |
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Keywords: | Glucose oxidase Silicon nitride Nanoparticles Direct voltammetry Biosensors |
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