Structural determination of a new 2(3 --> 20)abeotaxane with an unusual 13beta-substitution pattern and a new 6/8/6-ring taxane from Taxus cuspidata |
| |
| Authors: | Huo Changhong Su Xiaohui Li Xing Zhang Xiping Li Cunfang Wang Yufang Shi Qingwen Kiyota Hiromasa |
| |
| Affiliation: | Department of Medicinal Natural Product Chemistry, School of Pharmaceutical Sciences, Hebei Medical University, 361 Zhongshan East Road, 050017, Shijiazhuang, Hebei Province, P. R. China. |
| |
| Abstract: | A new 2(3 --> 20)abeotaxane with an unusual 13beta-substitution pattern and a new 6/8/6-ring taxane were isolated from the methanol extract of the needles of Taxus cuspidata. The structures were established as 2alpha,7beta-diacetoxy-5alpha,10beta,13beta-trihydroxy-2(3 --> 20)abeotaxa-4(20), 11-dien-9-one (1) and 2alpha,5alpha,7beta,9alpha,13alpha-pentahydroxy-10beta-acetoxytaxa-4(20),11-diene (2) on the basis of 1D and 2D NMR spectral data and high-resolution FAB-MS analyses. |
| |
| Keywords: | NMR 2D NMR 2α,7β‐diacetoxy‐5α,10β,13β‐trihydroxy‐2(3 → 20)abeotaxa‐4(20), 11‐dien‐9‐one, 2α,5α,7β,9α,13α‐pentahydroxy‐10β‐acetoxytaxa‐ 4(20), 11‐diene Taxus cuspidata Taxaceae taxane diterpenoid |
| 本文献已被 PubMed 等数据库收录！ |
|
