A novel microstep device for the size separation of cells |
| |
| Authors: | Vankrunkelsven Sarah Clicq David Pappaert Kris Ranson Willy De Tandt Cathleen Ottevaere Heidi Thienpont Hugo Baron Gino V Desmet Gert |
| |
| Institution: | Department of Chemical Engineering, Vrije Universiteit Brussel, Pleinlaan 2, B-1050 Brussels, Belgium. |
| |
| Abstract: | We report on a series of preliminary experiments investigating the applicability of a novel method for the size separation of nano- and microsized particles and cells. The working principle is based on the application of a shear-driven flow through stepwise tapered micro- or nanochannels. Size separations of mixtures of 0.5 and 1.0 microm carboxylated polystyrene beads as well as of binary mixtures of Staphylococcus aureus and Saccharomyces cerevisiae cells and of S. cerevisiae and Escherichia coli cells are demonstrated. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
|
