HPLC-Methods for Separation and Quantitation of Reserpin and its Main Degradation Products |
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Abstract: | Abstract An analytical method suitable for the stability control of dosage forms containing reserpine by HPLC is described. Besides reserpine the method quantitatively determines isoreserpine, 3,4-didehydroreserpine, trimethoxybenzoic acid, and renoxidine. The additional degradation products reserpic acid, and the secondary oxidation product 3,4,5,6-tetradehydroreserpine are qualitatively recorded. |
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