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A GPC Method for Analysis of Low Molecular Weight Drugs
Abstract:Abstract

Gel permeation chromatography has been shown as a versatile method for the analysis of low molecular weight drugs. Aspirin and its hydrolysis product, salicylic acid, which differ in a molecular weight of 42 units have been efficiently separated by a retention time difference of 3.25 minutes. Qualitative idea of other impurities is also obtained.
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