Liquid Chromatographic Analysis for Flecainide with Use of a Microbore Column and Ultraviolet Detection

Abstract

We describe a simple, isocratic high-performance liquid chromatographic method for measuring the oral antiarrhythmic agent flecainide acetate in serum or plasma. Sample analysis involves a simple organic extraction followed by chromatography on a microbore reverse phase column with ultraviolet detection at 298 nm.