HPLC Separation of Tautomeric Compounds of 4-Aminoisoxazolyl-1,2-naphthoquinones. II

Abstract

HPLC separations and quantitative analysis are described for a mixture of 4-aminoisoxazolyl-1,2-naph-thoquinone isomers. This assay is simple, rapid and stability indicating because the precursors and isomerization products can be monitored simultaneously. The results obtained are in agreement with those obtained by UV spectroscopy.