The Analysis of Toluene Diisocyanate and Diphenylmethane Diisocyanate by Gel Permeation Chromatography

Abstract

A gel permeation chromatographic method was developed for the quantitative analysis of toluene diisocyanate and diphenylmethane diisocyanate in polyurethane polymers. Standard curves were linear over the range of concentrations 2–35 μg/mL and a good correlation was established between the amount of diisocyanate injected and the peak height. In addition to rapid quantitation of diisocyanate monomers, the method developed also separates the polyurethane prepolymers and diisocyanate dimers and trimers, allowing analysis of components of commercial samples in a single step.